Biochem Ppt 56

BARRY UNIVERSITY COLLEGE OF HEALTH SCIENCES running SYLLABUS SPRING 2013 rails NUMBERBMS 528 secondment 01 COURSE NAMEBIOCHEMISTRY II TERM/YEARSpring 2013 (Jan. 9th, 2013 whitethorn 3rd, 2013) LECTURE ROOMHollywood Rm 2 LECTURE SCHEDULEFriday, 900 1200 p. m. INSTRUCTOR NAMEGraham Shaw, Ph. D. Professor OFFICE get over Wiegand 229 OFFICE TELEPHONE 305-899-3264 EMAIL emailprotected barry. edu OFFICE HOURSTuesday, 12. 30 3 p. m. Thursday, 12. 30 3 p. m. All other times by appointment COURSE DESCRIPTIONBiochemistry at Barry University is taught over two semesters, Biochemistry I in the finalise and Biochemistry II in the Spring. These curriculums have been designed so that when integrated they stick out the necessary biochemical knowledge for those in the medical and health related professions. The structure, figure out and metamorphosis of biologic entirelyy important molecules were reviewed in biochemistry I. Biochemistry II serves to systema skeletale on this substant ive whilst considering the application of biochemistry to affection etiology, diagnosis and treatment.Biochemistry II starts with a review of two areas crucial to normal, healthy cellular mattering. The structure and function of biological membranes, in spellicular the variety of cell signal transduction paradigms and the biochemistry of hormones. The structure, function and procreation of the cells genetic material. This information is reviewed in a series of lectures on DNA, the genetic cipher, protein subtraction and aspects of molecular biology. The digestion and absorption of biomolecules is reviewed and the consequences of break considered.A number of disease states are used to illustrate selected principles including the relationship amongst nutrition and disease atherosclerosis, hyperlipidemia, obesity and diabetes. The application of clinical biochemistry techniques to disease diagnosis is described and the biochemistry of exercise and aging visited. ARTICULATION T O MISSION OF THE UNIVERSITY This phase is offered by the College of Health Sciences, which is grounded in the liberal arts tradition and is a part of Barry Universitys scholarly community, committed to the highest academician standards in graduate education.This Biochemistry get across addresses both the university mission statement as intumesce as the strategical plan adapted by the College of Health Sciences. This is accomplished by pass a high quality scholarly person-centered curriculum in an environment, that encourages Christian and respectable values and promotes intellectual growth and curiosity. Throughout the semester students lead be promote to visit with faculty and demonstrate their critical thinking skills by pass opinions on current scientific theories and research reviews as they relate to Biochemistry.Case studies give be incorporated into lecture material and used to encourage student pursuit of knowledge and truth. Students in this course pass on devel op an sentience of health issues that impact those living within and outside of our community as they analyze nutrient deficiency diseases. The course will excessively cannonball along awareness for the well universe of others as the prevalence and etiology of metabolic disorders is addressed. COURSE GOALS At the end of this course, students should be able recall and apply biochemical principles to other courses throughout the curriculum, e. g. Pharmacology, Physiology. Students should be able to rationalize the significance of biochemistry in health and disease. COURSE OBJECTIVES At the end of the course, the student will be able to 1 Evaluate the structure and function of the plasma membrane. 2 Discriminate amidst the variety of signal transduction mechanisms. 3Explain the principles of DNA transcription and translation and evaluate the mechanisms by which protein synthesis is regulated. 4Discuss the digestion and absorption of biomolecules. 5Summarize the principles of clinic al biochemistry and organ function tests. 6Appraise the importance of biochemistry to disease etiology and diagnosis. TEACHING METHODS Each lecture will be presented victimization Powerpoint. Topical material not covered in the textual matter may be addressed in fall apart as appropriate, and is examinable. Where possible, time will be allowed for informal discussion of clinical scenarios and questions at the end of each(prenominal) class. Additional class materials, including case studies, and e-learning materials may also be post to the Blackboard learning environment as the course progresses, and students are also accountable for this material.An atmosphere of mutual respect will be reflected in all teaching/learning experiences COURSE TEXTS REQUIRED TEXT(S) Shaw, G. P. Biochemistry for Health Professionals. trey Edition, John Wiley. New York. 2011. EVALUATION CRITERIA There will be trey (3) quizzes and two (2) unit tests, a mid-term and a final. QUIZ I Jan eighteenth 10% QUIZ II Feb 22nd 10% QUIZ collar April 12th 10%MID-TERM TEST (Lecs 1 7) baby 1st 35% utmost EXAM (Lecs 8 14)May 3rd 35% TOTAL 100% endeavor OF brand Biochemistry II will be assessed by 3 quizzes, a mid-term examination and a final non-cumulative examination as indicated in the course schedule. Tests will be of one hour duration, and may contain material from class discussion, the Blackboard learning environment (including case studies) as well as the course text. Any questions you wish to challenge every from a quiz or a test, MUST BE IN piece of music and documented within 1 week of the key being posted.Tests and quizzes will not be returned and grades will not be rounded. GRADING outgo 100 90%A 89. 9 80%B 79. 9 70%C less than 70%F Grades will be posted on Blackboard. ACADEMIC DISHONESTY POLICY Ch take in or plagiarism will not be tolerated. A student who is caught either giving or receiving information or assistance during a interrogation session, quiz or examinati on will automatically receive the F grade and 0% on either the quiz or examination. The uniform consequence will apply to any(prenominal) proven case of plagiarism or communicating material on an examination to students in other section of the course.Furthermore, that individuals will be referred to the Dean for appropriate disciplinary action. handicap STATEMENT Students with documented special learning needs may extremity to inform the instructor so that accommodations may be made, or refer Barry Office of Services for students with Disabilities (305) 899-3489. STUDENT BEHAVIOR All Barry students are expect to behave according to accepted norms that ensure a climate wherein all can exercise their right to learn. Disruptive behavior is not gratifying in the classroom.Students engaging in such behavior may be asked to leave or may be removed from the class by security personnel. Actions such as violence, shouting, use of cell phones and/or beepers, use profanity, interruptin g, and any other behavior that the instructor believes creates an unpleasant environment in the classroom will be grounds for withdrawal from the course, judicial legal proceeding and/or failure in the course. FOOD/BEVERAGES Barry University has a policy of prohibiting eating and drinking within classroom space. PUNCTUALITY Students are expected to be on time for class. If you arrive later than 10 inutes after class has started, there is a possibility that the door will be locked. COURSE-SPECIFIC POLICIES attention Students are expected to attend all lectures and to take all tests and quizzes at the regularly scheduled time. Students should have completed the assigned reading in advance of class, and be prepared to discuss this at class time. just now by participating in class can the student gain ground a complete understanding of the concepts presented in the course objectives, course text and recommended readings. Attire for all lectures and examinations should be professiona l. Academic AssistanceAfter the inaugural exam those students receiving a grade below a C essential make an appointment with Dr. Shaw within one week of grade posting, for academic counseling. Excused absences from exams If any student is unable to attend an exam referable to illness (or other circumstances) he/she should notify Dr Shaw prior to the examination (or currently after) if at all possible. The student is responsible for submitting a physicians excuse. An excuse may be refused for chronic absentees. Once the absence has been excused, the student is also responsible for contacting the Dr Shaw to arrange a date and time to take the make-up exam.NOTE also-ran TO OBTAIN AN prune WILL RESULT IN A GRADE OF 0% FOR THE EXAM. LACK OF PREPARATION IS NOT CONSIDERED A VALID EXCUSE FOR MISSING AN EXAM. CHALLENGE POLICY Faculty will review all examinations in class with students, usually within 1 week of the grades being posted. This will not be a discussion session and any ques tions you wish to challenge either from a quiz or a test, MUST BE IN WRITING and documented within 1 week of the key being posted verbal challenges will not be accepted at any time. In the case of a challenge the final authority for accuracy will be the course text.Tests and quizzes will not be returned though they may be viewed by students with faculty approval. Make-Up Exam Policy Make-up exams can be of many types at the discretion of the instructor. Make-up exams will be given(p) after (not before) the regularly scheduled exam. If more than one person misses an exam, the make- up exams will be given simultaneously. Videotape Video and audiotape of Biochemistry classes is not permitted unless pass by faculty and the Office of Disability Services. Online lectures and e-learning materials will be purchasable for review from the Blackboard website.COURSE SCHEDULE Lecture No. Date Friday idea READING(Shaw) Chapter 1 11th Jan Membrane structure and functionCystic fibrosisG protei ns, Signal transduction 34 36 2 18thJan Quiz I (Lecture 1 plus e-learning materials) (10%)Deoxyribonucleic acidPreparation for DNA replicationDNA replication 37 39 3 25th Jan Mutations and DNA repairRNA and transcriptionThe genetic code 40 42 4 1st Feb Protein synthesisRegulation of protein synthesis in prokaryotesRegulation of protein synthesis in eukaryotes 43 45 5 8th Feb CancerInvestigating DNA 46 47 fifteenth Feb Principles of nutritionCalcium and osteoporosis 48 7 22nd Feb Fed, fasting & starvingIntegration of metabolism Digestion of dietary fatQUIZ II Lecture 6 plus e-learning materials) (10%) 49 51 8 1st Mar MID-TERM EXAMINATION (35%) (Lectures 1 7)Obesity Lipoproteins 52 53 SPRING BREAK MARCH 4th 8th 9 15th Mar Atherosclerosis and hypercholesterolemiaDigestion of carbohydratesDiabetes mellitusDiabetic complications 54 57 10 22nd Mar Protein digestion and absorptionIron metabolismHeme metabolism & Jaundice 58 60 29th Mar easter No Class 1 5th Apr Collagen Grow th factors and wound healingBlood clot & Clot dissolutionBlood tests and clinical scenario 61 64 12 12th Apr germ plasm proteinsOrgan function testsQUIZ III (Lecture 11 plus e-learning materials) (10%) 65 66 13 19thApr Enzyme diagnosticsAlcohol metabolism 67 68 14 26th Apr Exercise metabolismAging 69 70 May 3rd FINAL EXAMINATION(Lectures 8 15) 35 %300 pm 1 . Subject to change in extenuating circumstances